J Pediatr Intensive Care 2019; 08(03): 175-177
DOI: 10.1055/s-0039-1677815
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Dexmedetomidine to Treat 3, 4-Methylenedioxymethamphetamine-Induced Agitation in a 13-Month-Old Infant: A Case Report and Literature Review

Patricia J. L. T. Sanders
1   Section of Pediatric Intensive Care, Department of Pediatrics, Maastricht University Medical Center (MUMC + ), Maastricht, The Netherlands
,
Jan Hanot
1   Section of Pediatric Intensive Care, Department of Pediatrics, Maastricht University Medical Center (MUMC + ), Maastricht, The Netherlands
› Institutsangaben
Weitere Informationen

Publikationsverlauf

04. Oktober 2018

01. Januar 2019

Publikationsdatum:
13. Februar 2019 (online)

Preview

Abstract

We report a 13-month-old infant who accidentally ingested a tablet of 3, 4-methylenedioxymethamphetamine (MDMA) and was brought to the emergency department with tachycardia, seizures, mydriasis, and altered mental status. The patient received multiple doses of benzodiazepines to treat the seizures and developed respiratory insufficiency needing intubation. After extubation, the patient developed hyperactivity, myoclonic, and choreoathetoid movements which were unresponsive to benzodiazepines. Dexmedetomidine was started with good response. The patient made a full clinical recovery. This is the first case that illustrates the possibility to treat MDMA-induced agitation with dexmedetomidine in a 13-month-old infant.